TreeSummarizedExperiment: a S4 class for data with hierarchical structure

Data organized into hierarchical structures (e.g., phylogenies or cell types) arises in several biological fields. It is therefore of interest to have data containers that store the structure together with profile data, and provide functions easily access manipulate at different resolutions. Here, we present TreeSummarizedExperiment, a R/S4 class extends commonly used SingleCellExperiment by incorporating tree representations rows and/or columns (represented objects phylo class). follows convention SummarizedExperiment class, while providing links between assays nodes allow manipulation arbitrary levels tree. The package designed be extensible, allowing new on (phylo) contributed. As work based both which are popular classes many R packages, it expected able interact seamlessly other tools.